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Traduzione e analisi delle parole tramite l'intelligenza artificiale ChatGPT

In questa pagina puoi ottenere un'analisi dettagliata di una parola o frase, prodotta utilizzando la migliore tecnologia di intelligenza artificiale fino ad oggi:

come viene usata la parola
frequenza di utilizzo
è usato più spesso nel discorso orale o scritto
opzioni di traduzione delle parole
esempi di utilizzo (varie frasi con traduzione)
etimologia

Cosa (chi) è prodrug - definizione

COMPOUND THAT IS METABOLIZED INTO A PHARMACOLOGICALLY ACTIVE DRUG

Pro-drug; Prodrugs; In vivo conversion; Conversion in vivo; Inactive prodrug

prodrug

¦ noun a biologically inactive compound which can be metabolized in the body to produce a drug.

DEPT (medicine)

CDEPT; ADEPT (medicine); Antibody-directed enzyme prodrug therapy; GDEPT; VDEPT; Directed enzyme prodrug therapy; Directed Enzyme Prodrug Therapy

Directed enzyme prodrug therapy (DEPT) uses enzymes artificially introduced into the body to convert prodrugs, which have no or poor biologically activity, to the active form in the desired location within the body. Many chemotherapy drugs for cancer lack tumour specificity and the doses required to reach therapeutic levels in the tumour are often toxic to other tissues.

https://en.wikipedia.org/wiki/DEPT_(medicine)

Hypoxia-activated prodrug

HYPOXIA-ACTIVATED PRODUGS TARGET TUMOR REGIONS WHICH CELLS ARE MORE RESISTANT TO CONVENTIONAL CHEMOTHERAPY. THIS IS DUE TO A DEEPER POSITIONING FROM CAPILLARIES AND SLOWER CELL DIVISION PRODUCED BY THE LOW-OXYGEN ZONES, UNIDEAL FOR COMMON TREATMENTS.

Hypoxia activated prodrugs; Hypoxia-activated prodrugs

Hypoxia-Activated Prodrugs (HAPs) are prodrugs that target regions of tumor hypoxia within tumor cells. HAPs may offer the potential, alone and in combination with conventional chemotherapy, of improving cancer therapy.

https://en.wikipedia.org/wiki/Hypoxia-activated_prodrug

Wikipedia

Prodrug

A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug is absorbed, distributed, metabolized, and excreted (ADME).

Prodrugs are often designed to improve bioavailability when a drug itself is poorly absorbed from the gastrointestinal tract. A prodrug may be used to improve how selectively the drug interacts with cells or processes that are not its intended target. This reduces adverse or unintended effects of a drug, especially important in treatments like chemotherapy, which can have severe unintended and undesirable side effects.

https://en.wikipedia.org/wiki/Prodrug